Hannah Mamuszka and Lena Chaihorsky introduce the podcast. They discuss the financial misincentives that the U.S. healthcare is built on, which reward treatment over prevention and volume over value, keeping patients from the best data-driven care. Through their own careers in pharma, diagnostics, and laboratory medicine, they explain why data and science so often gets undervalued by the payment system, who benefits from our misaligned incentives and why now is the moment to start asking harder questions.